Elevates supine and standing heart rates and causes postural hypotension, it should be use with caution in elderly and in patients with hypertension and heart disease. Adverse Reactions: Cardiovascular: Hypotension and tachycardia
Cannabinoids have cardiovascular effects that include tachycardia, and transient changes in blood pressure, including episodes of postural hypotension. Use of SATIVEX® is not recommended in patients with pre-existing cardiovascular disease, such as ischaemic heart disease, arrhythmias, poorly controlled hypertension or severe heart failure.
Precautions: Heart disease and cardiac disorders Use with caution in patients with cardiac disorders because of occasional hypotension, possible hypertension, syncope or tachycardia.
Cannabinoids cause postural hypotension, but tolerance to the cardiovascular effects develops rapidly and together with adverse effects would preclude their consideration as a treatment for long-term use in hypertension Marihuana should be used with caution in patients with cardiac disorders because of occasional hypotension, possible hypertension, syncope, or tachycardia.